Holosiivska station opened to the public on December 15, 2010, as part of the Obolonsko-Teremkivska line, alongside Demiivska and Vasylkivska stations. Due to the challenging terrain and geological conditions, the station features a relatively low ceiling. To visually lift the space, special lights are positioned above each of the round columns on the platform.

The station has an island platform, with walls in the vestibules clad in white marble. The track walls are finished with light gray Akam-Pink granite, white marble, and green smalt. Notably, it was the first station in Ukraine to use a lattice suspended ceiling in its design.

Located directly beneath Holosiivska Square, the station provides easy access to public transportation and the nearby Maksym Rylskyi Holosiivskyi Park, thanks to an extensive network of underground passages.